Same here with a Xiaomi bluetooth mouse. Bluetooth keyboard working as usual.
Also pipewire using 100 per cent of one of the 8 cpu (threads)
Needed to apply a solution already posted consisting in to disable midi.
Created a nomid.config in /usr/share/wireplumber/wireplumber.conf.d/
wireplumber.profiles = {
main = {
monitor.alsa-midi = disabled
}
}