The developer of Pipeeffects has intended to switch to Pipewire for some time
[Feature Request] Adding support to Pipewire? · Issue #397 · wwmm/pulseeffects · GitHub
There has not been much discussion on here about pipewire so I do not know if anyone here is up to speed on troubleshooting Pipewire problems
Pipewire Wiki might have the information you need to work this out
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