Nautilus does not open itself when I am trying to open it from another program

I switched from KDE to GNOME and after changing the following file as I specified here, Nautilus works, but it does not work always.

This is my ~/.config/mimeapps.list file:

[Added Associations]
application/vnd.openxmlformats-officedocument.wordprocessingml.document=libreoffice-writer.desktop;
image/png=org.kde.gwenview.desktop;firefox.desktop;
inode/directory=org.gnome.nautilus.desktop;code-oss.desktop;
text/csv=freeoffice-planmaker.desktop;
x-scheme-handler/mailto=thunderbird.desktop;
x-scheme-handler/tg=userapp-Telegram Desktop-GU7MU0.desktop;
application/rss+xml=chromium.desktop;userapp-Thunderbird-W6UO00.desktop;
x-scheme-handler/news=userapp-Thunderbird-03CN00.desktop;
x-scheme-handler/snews=userapp-Thunderbird-03CN00.desktop;
x-scheme-handler/nntp=userapp-Thunderbird-03CN00.desktop;
x-scheme-handler/feed=userapp-Thunderbird-W6UO00.desktop;
application/x-extension-rss=userapp-Thunderbird-W6UO00.desktop;
image/svg+xml=org.inkscape.Inkscape.desktop;
application/msword=libreoffice-writer.desktop;
text/markdown=code_code.desktop;org.gnome.gedit.desktop;
text/css=code_code.desktop;
application/javascript=code_code.desktop;
text/plain=code_code.desktop;
application/pkix-cert=org.gnome.gedit.desktop;
image/jpeg=org.kde.gwenview.desktop;org.gnome.eog.desktop;
application/pdf=okularApplication_pdf.desktop;

[Default Applications]
image/png=org.kde.gwenview.desktop;
inode/directory=org.gnome.nautilus.desktop;
text/csv=freeoffice-planmaker.desktop;
x-scheme-handler/callto=Skype.desktop
x-scheme-handler/http=firefox.desktop;
x-scheme-handler/https=firefox.desktop;
x-scheme-handler/mailto=thunderbird.desktop;
x-scheme-handler/skype=Skype.desktop
x-scheme-handler/slack=Slack.desktop
x-scheme-handler/tel=org.kde.kdeconnect.handler.desktop
x-scheme-handler/tg=userapp-Telegram Desktop-GU7MU0.desktop
x-scheme-handler/workflowy=WorkFlowy.desktop
x-scheme-handler/news=userapp-Thunderbird-03CN00.desktop
x-scheme-handler/snews=userapp-Thunderbird-03CN00.desktop
x-scheme-handler/nntp=userapp-Thunderbird-03CN00.desktop
x-scheme-handler/feed=userapp-Thunderbird-W6UO00.desktop
application/rss+xml=userapp-Thunderbird-W6UO00.desktop
application/x-extension-rss=userapp-Thunderbird-W6UO00.desktop
x-scheme-handler/evernote=evernote-client.desktop

I tried to open Nautilus from VS Code, from Firefox, from Chromium, and it does not open, nor does an error appear to me. It seems to be doing nothing. But when I open it manually, from the dash or from the terminal, it opens well with nothing special, e.g. no error message in the terminal.

How can I make it open well?

Hello,

You should also look in /usr/share/applications/mimeinfo.cache

cat /usr/share/applications/mimeinfo.cache

Or simply edit it, and change the line:
inode/directory=visual-studio-code.desktop;org.gnome.Nautilus.desktop;
to
inode/directory=org.gnome.Nautilus.desktop;visual-studio-code.desktop;
or, instead of

inode/directory=org.gnome.Nautilus.desktop;code-oss.desktop;
or simply just use

inode/directory=org.gnome.Nautilus.desktop;

2 Likes

The requested file’s contents are:

[MIME Cache]
application/atom+xml=quiterss.desktop;
application/bzip2=org.gnome.FileRoller.desktop;org.gnome.Nautilus.desktop;
application/clarisworks=libreoffice-calc.desktop;libreoffice-draw.desktop;libreoffice-writer.desktop;
application/csv=libreoffice-calc.desktop;
application/epub+zip=okularApplication_epub.desktop;org.kde.mobile.okular_epub.desktop;
application/excel=freeoffice-planmaker.desktop;libreoffice-calc.desktop;
application/geopackage+sqlite3=sqlitebrowser.desktop;
application/gpx+xml=org.gnome.Maps.desktop;
application/gzip=org.gnome.FileRoller.desktop;org.gnome.Nautilus.desktop;org.kde.ark.desktop;
application/illustrator=org.gnome.Evince.desktop;org.inkscape.Inkscape.desktop;
application/java-archive=java-java-openjdk.desktop;
application/javascript=org.gnome.Builder.desktop;
application/json=firefox.desktop;org.gnome.Builder.desktop;org.kde.itinerary.desktop;
application/ld+json=org.kde.itinerary.desktop;
application/macwriteii=libreoffice-writer.desktop;
application/mathml+xml=libreoffice-math.desktop;
application/mbox=org.gnome.Evolution.desktop;
application/metalink+xml=org.kde.kget.desktop;
application/mpeg4-iod=vlc.desktop;
application/mpeg4-muxcodetable=vlc.desktop;
application/msexcel=libreoffice-calc.desktop;
application/mspowerpoint=freeoffice-presentations.desktop;libreoffice-impress.desktop;
application/msword=freeoffice-textmaker.desktop;libreoffice-writer.desktop;
application/mxf=org.gnome.Totem.desktop;vlc.desktop;
application/octet-stream=org.kde.kdeconnect_open.desktop;
application/ogg=audacity.desktop;vlc.desktop;
application/oxps=okularApplication_xps.desktop;org.gnome.Evince.desktop;org.kde.mobile.okular_xps.desktop;
application/pdf=chromium.desktop;firefox.desktop;gimp.desktop;google-chrome.desktop;libreoffice-draw.desktop;okularApplication_pdf.desktop;org.gnome.Evince.desktop;org.inkscape.Inkscape.desktop;org.kde.itinerary.desktop;org.kde.mobile.okular_pdf.desktop;
application/pkcs10=gcr-viewer.desktop;
application/pkcs10+pem=gcr-viewer.desktop;
application/pkcs12=gcr-viewer.desktop;
application/pkcs12+pem=gcr-viewer.desktop;
application/pkcs7-mime=gcr-viewer.desktop;
application/pkcs7-mime+pem=gcr-viewer.desktop;
application/pkcs8=gcr-viewer.desktop;
application/pkcs8+pem=gcr-viewer.desktop;
application/pkix-cert=gcr-viewer.desktop;
application/pkix-cert+pem=gcr-viewer.desktop;
application/pkix-crl=gcr-viewer.desktop;
application/pkix-crl+pem=gcr-viewer.desktop;
application/postscript=gimp.desktop;okularApplication_ghostview.desktop;org.gnome.Evince.desktop;org.inkscape.Inkscape.desktop;org.kde.mobile.okular_ghostview.desktop;
application/ppt=freeoffice-presentations.desktop;
application/prs.plucker=libreoffice-writer.desktop;okularApplication_plucker.desktop;org.kde.mobile.okular_plucker.desktop;
application/ram=org.gnome.Totem.desktop;vlc.desktop;
application/rdf+xml=chromium.desktop;google-chrome.desktop;quiterss.desktop;
application/rss+xml=chromium.desktop;google-chrome.desktop;quiterss.desktop;
application/rtf=freeoffice-textmaker.desktop;libreoffice-writer.desktop;
application/sdp=org.gnome.Totem.desktop;vlc.desktop;
application/smil=org.gnome.Totem.desktop;
application/smil+xml=org.gnome.Totem.desktop;
application/sqlitebrowser=sqlitebrowser.desktop;
application/tab-separated-values=libreoffice-calc.desktop;
application/visio=org.inkscape.Inkscape.desktop;
application/visio.drawing=org.inkscape.Inkscape.desktop;
application/vnd.android.package-archive=org.gnome.FileRoller.desktop;
application/vnd.appimage=appimagelauncher.desktop;
application/vnd.apple.mpegurl=org.gnome.Totem.desktop;vlc.desktop;
application/vnd.apple.pkpass=org.kde.itinerary.desktop;
application/vnd.comicbook+zip=org.gnome.Evince.desktop;
application/vnd.comicbook-rar=org.gnome.Evince.desktop;
application/vnd.corel-draw=libreoffice-draw.desktop;org.inkscape.Inkscape.desktop;
application/vnd.db4s-project+xml=sqlitebrowser.desktop;
application/vnd.debian.binary-package=org.gnome.FileRoller.desktop;org.kde.ark.desktop;
application/vnd.flatpak=gnome-software-local-file.desktop;
application/vnd.flatpak.ref=gnome-software-local-file.desktop;
application/vnd.flatpak.repo=gnome-software-local-file.desktop;
application/vnd.geo+json=org.gnome.Maps.desktop;
application/vnd.gnome.recipes.export=org.gnome.Recipes.desktop;
application/vnd.google-earth.kml+xml=org.gnome.Maps.desktop;
application/vnd.iccprofile=gcm-import.desktop;
application/vnd.kde.bluedevil-sendfile=org.kde.bluedevilsendfile.desktop;
application/vnd.kde.fontspackage=org.kde.kfontview.desktop;
application/vnd.kde.itinerary=org.kde.itinerary.desktop;
application/vnd.kde.okular-archive=org.kde.okular.desktop;
application/vnd.lotus-1-2-3=libreoffice-calc.desktop;
application/vnd.lotus-wordpro=libreoffice-writer.desktop;
application/vnd.ms-asf=org.gnome.Totem.desktop;vlc.desktop;
application/vnd.ms-cab-compressed=gnome-software-local-file.desktop;org.gnome.FileRoller.desktop;org.kde.ark.desktop;
application/vnd.ms-excel=freeoffice-planmaker.desktop;libreoffice-calc.desktop;
application/vnd.ms-excel.sheet.binary.macroEnabled.12=libreoffice-calc.desktop;
application/vnd.ms-excel.sheet.macroEnabled.12=libreoffice-calc.desktop;
application/vnd.ms-excel.sheet.macroenabled.12=freeoffice-planmaker.desktop;
application/vnd.ms-excel.template.macroEnabled.12=libreoffice-calc.desktop;
application/vnd.ms-excel.template.macroenabled.12=freeoffice-planmaker.desktop;
application/vnd.ms-powerpoint=freeoffice-presentations.desktop;libreoffice-impress.desktop;
application/vnd.ms-powerpoint.presentation.macroEnabled.12=libreoffice-impress.desktop;
application/vnd.ms-powerpoint.presentation.macroenabled.12=freeoffice-presentations.desktop;
application/vnd.ms-powerpoint.slideshow.macroEnabled.12=freeoffice-presentations.desktop;libreoffice-impress.desktop;
application/vnd.ms-powerpoint.template.macroEnabled.12=libreoffice-impress.desktop;
application/vnd.ms-powerpoint.template.macroenabled.12=freeoffice-presentations.desktop;
application/vnd.ms-publisher=libreoffice-draw.desktop;
application/vnd.ms-word=freeoffice-textmaker.desktop;libreoffice-writer.desktop;
application/vnd.ms-word.document.macroEnabled.12=libreoffice-writer.desktop;
application/vnd.ms-word.document.macroenabled.12=freeoffice-textmaker.desktop;
application/vnd.ms-word.template.macroEnabled.12=libreoffice-writer.desktop;
application/vnd.ms-word.template.macroenabled.12=freeoffice-textmaker.desktop;
application/vnd.ms-works=libreoffice-calc.desktop;libreoffice-writer.desktop;
application/vnd.ms-wpl=org.gnome.Totem.desktop;vlc.desktop;
application/vnd.ms-xpsdocument=okularApplication_xps.desktop;org.gnome.Evince.desktop;org.kde.mobile.okular_xps.desktop;
application/vnd.nintendo.snes.rom=org.gnome.Games.desktop;
application/vnd.oasis.opendocument.chart=libreoffice-calc.desktop;
application/vnd.oasis.opendocument.chart-template=libreoffice-calc.desktop;
application/vnd.oasis.opendocument.database=libreoffice-base.desktop;
application/vnd.oasis.opendocument.formula=libreoffice-math.desktop;
application/vnd.oasis.opendocument.formula-template=libreoffice-math.desktop;
application/vnd.oasis.opendocument.graphics=libreoffice-draw.desktop;
application/vnd.oasis.opendocument.graphics-flat-xml=libreoffice-draw.desktop;libreoffice-xsltfilter.desktop;
application/vnd.oasis.opendocument.graphics-template=libreoffice-draw.desktop;
application/vnd.oasis.opendocument.presentation=libreoffice-impress.desktop;
application/vnd.oasis.opendocument.presentation-flat-xml=libreoffice-impress.desktop;libreoffice-xsltfilter.desktop;
application/vnd.oasis.opendocument.presentation-template=libreoffice-impress.desktop;
application/vnd.oasis.opendocument.spreadsheet=libreoffice-calc.desktop;
application/vnd.oasis.opendocument.spreadsheet-flat-xml=libreoffice-calc.desktop;libreoffice-xsltfilter.desktop;
application/vnd.oasis.opendocument.spreadsheet-template=libreoffice-calc.desktop;
application/vnd.oasis.opendocument.text=freeoffice-textmaker.desktop;libreoffice-writer.desktop;
application/vnd.oasis.opendocument.text-flat-xml=libreoffice-writer.desktop;libreoffice-xsltfilter.desktop;
application/vnd.oasis.opendocument.text-master=libreoffice-writer.desktop;
application/vnd.oasis.opendocument.text-master-template=libreoffice-writer.desktop;
application/vnd.oasis.opendocument.text-template=freeoffice-textmaker.desktop;libreoffice-writer.desktop;
application/vnd.oasis.opendocument.text-web=libreoffice-writer.desktop;
application/vnd.openofficeorg.extension=libreoffice-startcenter.desktop;
application/vnd.openxmlformats-officedocument.presentationml.presentation=freeoffice-presentations.desktop;libreoffice-impress.desktop;
application/vnd.openxmlformats-officedocument.presentationml.slide=libreoffice-impress.desktop;
application/vnd.openxmlformats-officedocument.presentationml.slideshow=freeoffice-presentations.desktop;libreoffice-impress.desktop;
application/vnd.openxmlformats-officedocument.presentationml.template=freeoffice-presentations.desktop;libreoffice-impress.desktop;
application/vnd.openxmlformats-officedocument.spreadsheetml.sheet=freeoffice-planmaker.desktop;libreoffice-calc.desktop;
application/vnd.openxmlformats-officedocument.spreadsheetml.template=freeoffice-planmaker.desktop;libreoffice-calc.desktop;
application/vnd.openxmlformats-officedocument.wordprocessingml.document=freeoffice-textmaker.desktop;libreoffice-writer.desktop;
application/vnd.openxmlformats-officedocument.wordprocessingml.template=freeoffice-textmaker.desktop;libreoffice-writer.desktop;
application/vnd.palm=libreoffice-writer.desktop;
application/vnd.rar=org.gnome.Nautilus.desktop;org.kde.ark.desktop;
application/vnd.rn-realmedia=org.gnome.Totem.desktop;vlc.desktop;
application/vnd.rn-realmedia-vbr=org.gnome.Totem.desktop;vlc.desktop;
application/vnd.snap=gnome-software-local-file.desktop;
application/vnd.sqlite3=sqlitebrowser.desktop;
application/vnd.stardivision.calc=freeoffice-planmaker.desktop;
application/vnd.stardivision.writer=freeoffice-textmaker.desktop;
application/vnd.stardivision.writer-global=libreoffice-writer.desktop;
application/vnd.sun.xml.base=libreoffice-base.desktop;
application/vnd.sun.xml.calc=libreoffice-calc.desktop;
application/vnd.sun.xml.calc.template=libreoffice-calc.desktop;
application/vnd.sun.xml.draw=libreoffice-draw.desktop;
application/vnd.sun.xml.draw.template=libreoffice-draw.desktop;
application/vnd.sun.xml.impress=libreoffice-impress.desktop;
application/vnd.sun.xml.impress.template=libreoffice-impress.desktop;
application/vnd.sun.xml.math=libreoffice-math.desktop;
application/vnd.sun.xml.writer=freeoffice-textmaker.desktop;libreoffice-writer.desktop;
application/vnd.sun.xml.writer.global=libreoffice-writer.desktop;
application/vnd.sun.xml.writer.template=freeoffice-textmaker.desktop;libreoffice-writer.desktop;
application/vnd.visio=libreoffice-draw.desktop;org.inkscape.Inkscape.desktop;
application/vnd.wordperfect=libreoffice-writer.desktop;
application/vsd=org.inkscape.Inkscape.desktop;
application/wordperfect=libreoffice-writer.desktop;
application/x-123=libreoffice-calc.desktop;
application/x-7z-compressed=org.gnome.FileRoller.desktop;org.gnome.Nautilus.desktop;org.kde.ark.desktop;
application/x-7z-compressed-tar=org.gnome.FileRoller.desktop;org.gnome.Nautilus.desktop;
application/x-abiword=libreoffice-writer.desktop;
application/x-ace=org.gnome.FileRoller.desktop;
application/x-alpm-package=pamac-installer.desktop;
application/x-alz=org.gnome.FileRoller.desktop;
application/x-amiga-disk-format=org.gnome.Games.desktop;
application/x-aportisdoc=libreoffice-writer.desktop;
application/x-app-package=gnome-software-local-file.desktop;
application/x-appimage=appimagelauncher.desktop;
application/x-ar=org.gnome.FileRoller.desktop;
application/x-archive=org.gnome.FileRoller.desktop;org.kde.ark.desktop;
application/x-arj=org.gnome.FileRoller.desktop;
application/x-atari-2600-rom=org.gnome.Games.desktop;
application/x-atari-7800-rom=org.gnome.Games.desktop;
application/x-atari-lynx-rom=org.gnome.Games.desktop;
application/x-audacity-project=audacity.desktop;
application/x-bcpio=org.kde.ark.desktop;
application/x-bittorrent=org.kde.kget.desktop;org.qbittorrent.qBittorrent.desktop;
application/x-brotli=org.gnome.FileRoller.desktop;
application/x-bzdvi=okularApplication_dvi.desktop;org.gnome.Evince.desktop;org.kde.mobile.okular_dvi.desktop;
application/x-bzip=org.gnome.FileRoller.desktop;org.gnome.Nautilus.desktop;org.kde.ark.desktop;
application/x-bzip-brotli-tar=org.gnome.FileRoller.desktop;
application/x-bzip-compressed-tar=org.gnome.FileRoller.desktop;org.gnome.Nautilus.desktop;org.kde.ark.desktop;
application/x-bzip1=org.gnome.FileRoller.desktop;
application/x-bzip1-compressed-tar=org.gnome.FileRoller.desktop;
application/x-bzpdf=okularApplication_pdf.desktop;org.gnome.Evince.desktop;org.kde.mobile.okular_pdf.desktop;
application/x-bzpostscript=okularApplication_ghostview.desktop;org.gnome.Evince.desktop;org.kde.mobile.okular_ghostview.desktop;
application/x-cabinet=org.gnome.FileRoller.desktop;
application/x-cb7=okularApplication_comicbook.desktop;org.gnome.Evince.desktop;org.kde.mobile.okular_comicbook.desktop;
application/x-cbr=okularApplication_comicbook.desktop;org.gnome.Evince.desktop;org.kde.mobile.okular_comicbook.desktop;
application/x-cbt=okularApplication_comicbook.desktop;org.gnome.Evince.desktop;org.kde.mobile.okular_comicbook.desktop;
application/x-cbz=okularApplication_comicbook.desktop;org.gnome.Evince.desktop;org.kde.mobile.okular_comicbook.desktop;
application/x-cd-image=gnome-disk-image-mounter.desktop;gnome-disk-image-writer.desktop;org.gnome.Boxes.desktop;org.gnome.FileRoller.desktop;org.kde.ark.desktop;org.kde.k3b.desktop;vlc.desktop;
application/x-chess-pgn=org.gnome.Chess.desktop;
application/x-chm=okularApplication_chm.desktop;org.kde.mobile.okular_chm.desktop;
application/x-chrome-extension=org.gnome.FileRoller.desktop;
application/x-cmakecache=cmake-gui.desktop;
application/x-compress=org.gnome.FileRoller.desktop;org.gnome.Nautilus.desktop;org.kde.ark.desktop;
application/x-compressed-tar=org.gnome.FileRoller.desktop;org.gnome.Nautilus.desktop;org.kde.ark.desktop;
application/x-cpio=org.gnome.FileRoller.desktop;org.gnome.Nautilus.desktop;org.kde.ark.desktop;
application/x-cpio-compressed=org.kde.ark.desktop;
application/x-cue=org.gnome.Games.desktop;org.kde.k3b.desktop;
application/x-dbase=libreoffice-calc.desktop;
application/x-dbf=libreoffice-calc.desktop;
application/x-deb=gnome-software-local-file.desktop;org.gnome.FileRoller.desktop;org.kde.ark.desktop;
application/x-designer=designer.desktop;
application/x-desktop=org.gnome.Builder.desktop;
application/x-discjuggler-cd-image=org.gnome.Games.desktop;
application/x-doc=freeoffice-textmaker.desktop;libreoffice-writer.desktop;
application/x-doom-wad=org.gnome.Games.desktop;
application/x-dos_ms_excel=libreoffice-calc.desktop;
application/x-dvi=okularApplication_dvi.desktop;org.gnome.Evince.desktop;org.kde.mobile.okular_dvi.desktop;
application/x-ear=org.gnome.FileRoller.desktop;
application/x-excel=freeoffice-planmaker.desktop;libreoffice-calc.desktop;
application/x-ext-cb7=org.gnome.Evince.desktop;
application/x-ext-cbr=org.gnome.Evince.desktop;
application/x-ext-cbt=org.gnome.Evince.desktop;
application/x-ext-cbz=org.gnome.Evince.desktop;
application/x-ext-djv=org.gnome.Evince.desktop;
application/x-ext-djvu=org.gnome.Evince.desktop;
application/x-ext-dvi=org.gnome.Evince.desktop;
application/x-ext-eps=org.gnome.Evince.desktop;
application/x-ext-pdf=org.gnome.Evince.desktop;
application/x-ext-ps=org.gnome.Evince.desktop;
application/x-extension-m4a=org.gnome.Totem.desktop;vlc.desktop;
application/x-extension-mp4=org.gnome.Totem.desktop;vlc.desktop;
application/x-extension-txt=libreoffice-writer.desktop;
application/x-fds-disk=org.gnome.Games.desktop;
application/x-fictionbook+xml=libreoffice-writer.desktop;okularApplication_fb.desktop;org.kde.mobile.okular_fb.desktop;
application/x-flac=vlc.desktop;
application/x-flash-video=org.gnome.Totem.desktop;vlc.desktop;
application/x-font-bdf=org.kde.kfontview.desktop;
application/x-font-otf=org.gnome.font-viewer.desktop;org.kde.kfontview.desktop;
application/x-font-pcf=org.gnome.font-viewer.desktop;org.kde.kfontview.desktop;
application/x-font-ttf=org.gnome.font-viewer.desktop;org.kde.kfontview.desktop;
application/x-font-type1=org.gnome.font-viewer.desktop;org.kde.kfontview.desktop;
application/x-freemind=freemind.desktop;
application/x-gameboy-color-rom=org.gnome.Games.desktop;
application/x-gameboy-rom=org.gnome.Games.desktop;
application/x-gamecube-rom=org.gnome.Games.desktop;
application/x-gamegear-rom=org.gnome.Games.desktop;
application/x-gba-rom=org.gnome.Games.desktop;
application/x-gd-rom-cue=org.gnome.Games.desktop;
application/x-genesis-32x-rom=org.gnome.Games.desktop;
application/x-genesis-rom=org.gnome.Games.desktop;
application/x-glade=org.gnome.Glade.desktop;
application/x-gnome-app-info=org.gnome.Builder.desktop;
application/x-gtar=org.gnome.FileRoller.desktop;
application/x-gtk-builder=org.gnome.Glade.desktop;
application/x-gzdvi=okularApplication_dvi.desktop;org.gnome.Evince.desktop;org.kde.mobile.okular_dvi.desktop;
application/x-gzip=org.gnome.FileRoller.desktop;org.gnome.Nautilus.desktop;
application/x-gzpdf=okularApplication_pdf.desktop;org.gnome.Evince.desktop;org.kde.mobile.okular_pdf.desktop;
application/x-gzpostscript=okularApplication_ghostview.desktop;org.gnome.Evince.desktop;org.gnome.FileRoller.desktop;org.kde.mobile.okular_ghostview.desktop;
application/x-homebank=homebank.desktop;
application/x-hwp=libreoffice-writer.desktop;
application/x-iso=org.kde.k3b.desktop;
application/x-iso9660-appimage=appimagelauncher.desktop;org.kde.ark.desktop;
application/x-iwork-keynote-sffkey=libreoffice-impress.desktop;
application/x-iwork-numbers-sffnumbers=libreoffice-calc.desktop;
application/x-iwork-pages-sffpages=libreoffice-writer.desktop;
application/x-jar=java-java-openjdk.desktop;
application/x-java-archive=java-java-openjdk.desktop;org.gnome.FileRoller.desktop;org.kde.ark.desktop;
application/x-javascript=org.gnome.Builder.desktop;
application/x-k3b=org.kde.k3b.desktop;
application/x-kdenlive=org.kde.kdenlive.desktop;
application/x-keepass2=org.keepassxc.KeePassXC.desktop;
application/x-krita=org.kde.gwenview.desktop;
application/x-ksysguard=org.kde.ksysguard.desktop;
application/x-kwallet=org.kde.kwalletmanager5.desktop;
application/x-lha=org.gnome.FileRoller.desktop;org.gnome.Nautilus.desktop;org.kde.ark.desktop;
application/x-lhz=org.gnome.FileRoller.desktop;
application/x-linguist=linguist.desktop;
application/x-love-game=org.gnome.Games.desktop;
application/x-lrzip=org.gnome.FileRoller.desktop;
application/x-lrzip-compressed-tar=org.gnome.FileRoller.desktop;org.kde.ark.desktop;
application/x-lz4=org.gnome.FileRoller.desktop;
application/x-lz4-compressed-tar=org.gnome.FileRoller.desktop;org.kde.ark.desktop;
application/x-lzip=org.gnome.FileRoller.desktop;org.gnome.Nautilus.desktop;
application/x-lzip-compressed-tar=org.gnome.FileRoller.desktop;org.gnome.Nautilus.desktop;org.kde.ark.desktop;
application/x-lzma=org.gnome.FileRoller.desktop;org.gnome.Nautilus.desktop;org.kde.ark.desktop;
application/x-lzma-compressed-tar=org.gnome.FileRoller.desktop;org.gnome.Nautilus.desktop;org.kde.ark.desktop;
application/x-lzop=org.gnome.FileRoller.desktop;
application/x-m4=org.gnome.Builder.desktop;
application/x-mame-rom=org.gnome.Games.desktop;
application/x-matroska=org.gnome.Totem.desktop;vlc.desktop;
application/x-meld-comparison=org.gnome.meld.desktop;
application/x-mimearchive=org.gnome.Epiphany.desktop;
application/x-mobipocket-ebook=okularApplication_mobi.desktop;org.kde.mobile.okular_mobi.desktop;
application/x-ms-dos-executable=org.gnome.FileRoller.desktop;org.gnome.Games.desktop;
application/x-ms-excel=freeoffice-planmaker.desktop;libreoffice-calc.desktop;
application/x-ms-wim=org.gnome.FileRoller.desktop;
application/x-msexcel=freeoffice-planmaker.desktop;libreoffice-calc.desktop;
application/x-mswrite=libreoffice-writer.desktop;
application/x-n64-rom=org.gnome.Games.desktop;
application/x-neo-geo-pocket-color-rom=org.gnome.Games.desktop;
application/x-neo-geo-pocket-rom=org.gnome.Games.desktop;
application/x-nes-rom=org.gnome.Games.desktop;
application/x-netshow-channel=org.gnome.Totem.desktop;
application/x-nintendo-3ds-executable=org.gnome.Games.desktop;
application/x-nintendo-3ds-rom=org.gnome.Games.desktop;
application/x-nintendo-ds-rom=org.gnome.Games.desktop;
application/x-ogg=vlc.desktop;
application/x-pagemaker=libreoffice-draw.desktop;
application/x-pc-engine-rom=org.gnome.Games.desktop;
application/x-pem-file=gcr-viewer.desktop;
application/x-pem-key=gcr-viewer.desktop;
application/x-perl=org.gnome.Builder.desktop;
application/x-php=org.gnome.Builder.desktop;
application/x-php-source=org.gnome.Builder.desktop;
application/x-pkcs12=gcr-viewer.desktop;
application/x-pkcs7-certificates=gcr-viewer.desktop;
application/x-playstation-rom=org.gnome.Games.desktop;
application/x-pmd=freeoffice-planmaker.desktop;
application/x-pmv=freeoffice-planmaker.desktop;
application/x-pocket-word=freeoffice-textmaker.desktop;
application/x-prd=freeoffice-presentations.desktop;
application/x-prs=freeoffice-presentations.desktop;
application/x-prv=freeoffice-presentations.desktop;
application/x-python=org.gnome.Builder.desktop;
application/x-quattropro=libreoffice-calc.desktop;
application/x-quicktime-media-link=org.gnome.Totem.desktop;vlc.desktop;
application/x-quicktimeplayer=org.gnome.Totem.desktop;vlc.desktop;
application/x-rar=org.gnome.FileRoller.desktop;org.kde.ark.desktop;
application/x-rar-compressed=org.gnome.FileRoller.desktop;
application/x-raw-disk-image=gnome-disk-image-mounter.desktop;gnome-disk-image-writer.desktop;
application/x-raw-disk-image-xz-compressed=gnome-disk-image-writer.desktop;
application/x-redhat-package-manager=gnome-software-local-file.desktop;
application/x-rpm=gnome-software-local-file.desktop;org.gnome.FileRoller.desktop;org.kde.ark.desktop;
application/x-ruby=org.gnome.Builder.desktop;
application/x-rzip=org.gnome.FileRoller.desktop;
application/x-rzip-compressed-tar=org.gnome.FileRoller.desktop;
application/x-saturn-rom=org.gnome.Games.desktop;
application/x-sega-cd-rom=org.gnome.Games.desktop;
application/x-sega-pico-rom=org.gnome.Games.desktop;
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application/x-shellscript=emacs.desktop;gvim.desktop;nvim.desktop;org.gnome.Builder.desktop;vim.desktop;
application/x-shockwave-flash=vlc.desktop;
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application/x-smil=org.gnome.Totem.desktop;
application/x-sms-rom=org.gnome.Games.desktop;
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application/x-source-rpm=org.gnome.FileRoller.desktop;org.kde.ark.desktop;
application/x-spkac=gcr-viewer.desktop;
application/x-spkac+base64=gcr-viewer.desktop;
application/x-sqlite2=sqlitebrowser.desktop;
application/x-sqlite3=sqlitebrowser.desktop;
application/x-sqlitebrowser=sqlitebrowser.desktop;
application/x-starcalc=libreoffice-calc.desktop;
application/x-stardraw=libreoffice-draw.desktop;
application/x-starwriter=libreoffice-writer.desktop;
application/x-stuffit=org.gnome.FileRoller.desktop;
application/x-sv4cpio=org.kde.ark.desktop;
application/x-sv4crc=org.kde.ark.desktop;
application/x-sylk=freeoffice-planmaker.desktop;
application/x-sysprof-capture=org.gnome.Sysprof3.desktop;
application/x-t602=libreoffice-writer.desktop;
application/x-tar=org.gnome.FileRoller.desktop;org.gnome.Nautilus.desktop;org.kde.ark.desktop;
application/x-tarz=org.gnome.FileRoller.desktop;org.gnome.Nautilus.desktop;org.kde.ark.desktop;
application/x-tmd=freeoffice-textmaker.desktop;
application/x-tmv=freeoffice-textmaker.desktop;
application/x-tzo=org.gnome.FileRoller.desktop;org.kde.ark.desktop;
application/x-virtual-boy-rom=org.gnome.Games.desktop;
application/x-visio=org.inkscape.Inkscape.desktop;
application/x-vnc=org.gnome.Connections.desktop;
application/x-vsd=org.inkscape.Inkscape.desktop;
application/x-war=org.gnome.FileRoller.desktop;
application/x-wii-rom=org.gnome.Games.desktop;
application/x-wii-wad=org.gnome.Games.desktop;
application/x-wonderswan-color-rom=org.gnome.Games.desktop;
application/x-wonderswan-rom=org.gnome.Games.desktop;
application/x-wpg=libreoffice-draw.desktop;
application/x-wwf=okularApplication_pdf.desktop;org.kde.mobile.okular_pdf.desktop;
application/x-x509-ca-cert=gcr-viewer.desktop;
application/x-x509-user-cert=gcr-viewer.desktop;
application/x-xar=org.gnome.FileRoller.desktop;org.gnome.Nautilus.desktop;org.kde.ark.desktop;
application/x-xccx=org.inkscape.Inkscape.desktop;
application/x-xcdt=org.inkscape.Inkscape.desktop;
application/x-xcgm=org.inkscape.Inkscape.desktop;
application/x-xcmx=org.inkscape.Inkscape.desktop;
application/x-xls=freeoffice-planmaker.desktop;
application/x-xpinstall=firefox.desktop;org.gnome.Epiphany.desktop;thunderbird.desktop;
application/x-xsk1=org.inkscape.Inkscape.desktop;
application/x-xz=org.gnome.FileRoller.desktop;org.gnome.Nautilus.desktop;org.kde.ark.desktop;
application/x-xz-compressed-tar=org.gnome.FileRoller.desktop;org.gnome.Nautilus.desktop;org.kde.ark.desktop;
application/x-xzpdf=org.gnome.Evince.desktop;
application/x-yaml=org.gnome.Builder.desktop;
application/x-zip=org.gnome.FileRoller.desktop;
application/x-zip-compressed=org.gnome.FileRoller.desktop;
application/x-zoo=org.gnome.FileRoller.desktop;
application/x-zstd-compressed-tar=org.gnome.FileRoller.desktop;org.kde.ark.desktop;
application/xhtml+xml=chromium.desktop;firefox.desktop;google-chrome.desktop;org.gnome.Epiphany.desktop;
application/xhtml_xml=chromium.desktop;google-chrome.desktop;
application/xls=freeoffice-planmaker.desktop;
application/xml=chromium.desktop;google-chrome.desktop;org.gnome.Builder.desktop;
application/xspf+xml=vlc.desktop;
application/zip=org.gnome.FileRoller.desktop;org.gnome.Games.desktop;org.gnome.Nautilus.desktop;org.kde.ark.desktop;
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audio/3gpp=vlc.desktop;
audio/3gpp2=vlc.desktop;
audio/AMR=vlc.desktop;
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audio/midi=vlc.desktop;
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audio/opus=vlc.desktop;
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audio/vnd.dolby.heaac.1=vlc.desktop;
audio/vnd.dolby.heaac.2=vlc.desktop;
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audio/vnd.dts.hd=vlc.desktop;
audio/vnd.rn-realaudio=vlc.desktop;
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audio/wav=vlc.desktop;
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audio/x-matroska=vlc.desktop;
audio/x-mod=vlc.desktop;
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audio/x-ms-asx=vlc.desktop;
audio/x-ms-wax=vlc.desktop;
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audio/x-musepack=vlc.desktop;
audio/x-pn-aiff=vlc.desktop;
audio/x-pn-au=vlc.desktop;
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audio/x-pn-realaudio-plugin=vlc.desktop;
audio/x-pn-wav=vlc.desktop;
audio/x-pn-windows-acm=vlc.desktop;
audio/x-real-audio=vlc.desktop;
audio/x-realaudio=vlc.desktop;
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audio/x-speex=vlc.desktop;
audio/x-tta=vlc.desktop;
audio/x-vorbis=vlc.desktop;
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audio/x-wav=audacity.desktop;vlc.desktop;
audio/x-wavpack=vlc.desktop;
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font/otf=org.gnome.font-viewer.desktop;org.kde.kfontview.desktop;
font/ttf=org.gnome.font-viewer.desktop;org.kde.kfontview.desktop;
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image/vnd.djvu=okularApplication_djvu.desktop;org.kde.mobile.okular_djvu.desktop;
image/vnd.djvu+multipage=org.gnome.Evince.desktop;
image/vnd.rn-realpix=org.gnome.Totem.desktop;vlc.desktop;
image/vnd.wap.wbmp=org.gnome.eog.desktop;
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image/x-bmp=org.gnome.eog.desktop;
image/x-bzeps=okularApplication_ghostview.desktop;okularApplication_kimgio.desktop;org.gnome.Evince.desktop;org.kde.mobile.okular_ghostview.desktop;org.kde.mobile.okular_kimgio.desktop;
image/x-canon-cr2=org.kde.gwenview.desktop;
image/x-canon-crw=org.kde.gwenview.desktop;
image/x-compressed-xcf=gimp.desktop;
image/x-dds=okularApplication_kimgio.desktop;org.kde.mobile.okular_kimgio.desktop;
image/x-emf=libreoffice-draw.desktop;
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image/x-exr=gimp.desktop;okularApplication_kimgio.desktop;org.kde.mobile.okular_kimgio.desktop;
image/x-fits=gimp.desktop;
image/x-freehand=libreoffice-draw.desktop;
image/x-fuji-raf=org.kde.gwenview.desktop;
image/x-gimp-gbr=gimp.desktop;
image/x-gimp-gih=gimp.desktop;
image/x-gimp-pat=gimp.desktop;
image/x-gray=org.gnome.eog.desktop;
image/x-gzeps=okularApplication_ghostview.desktop;okularApplication_kimgio.desktop;org.gnome.Evince.desktop;org.kde.mobile.okular_ghostview.desktop;org.kde.mobile.okular_kimgio.desktop;
image/x-hdr=okularApplication_kimgio.desktop;org.kde.mobile.okular_kimgio.desktop;
image/x-icb=org.gnome.eog.desktop;
image/x-icns=org.gnome.eog.desktop;org.kde.gwenview.desktop;
image/x-ico=okularApplication_kimgio.desktop;org.gnome.eog.desktop;org.kde.gwenview.desktop;org.kde.mobile.okular_kimgio.desktop;
image/x-icon=gimp.desktop;
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image/x-kodak-dcr=org.kde.gwenview.desktop;
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image/x-minolta-mrw=org.kde.gwenview.desktop;
image/x-nikon-nef=org.kde.gwenview.desktop;
image/x-olympus-orf=org.kde.gwenview.desktop;
image/x-panasonic-rw=org.kde.gwenview.desktop;
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image/x-pentax-pef=org.kde.gwenview.desktop;
image/x-pict=org.gnome.Totem.desktop;
image/x-png=org.gnome.eog.desktop;
image/x-portable-anymap=gimp.desktop;org.gnome.eog.desktop;
image/x-portable-bitmap=gimp.desktop;okularApplication_kimgio.desktop;org.gnome.eog.desktop;org.kde.gwenview.desktop;org.kde.mobile.okular_kimgio.desktop;
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image/x-xwindowdump=gimp.desktop;
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message/rfc822=org.gnome.Epiphany.desktop;org.gnome.Evolution.desktop;org.kde.itinerary.desktop;thunderbird.desktop;
misc/ultravox=org.gnome.Totem.desktop;vlc.desktop;
multipart/related=org.gnome.Epiphany.desktop;
text/calendar=org.gnome.Evolution.desktop;org.kde.itinerary.desktop;
text/comma-separated-values=libreoffice-calc.desktop;
text/css=org.gnome.Builder.desktop;
text/csv=libreoffice-calc.desktop;
text/directory=org.gnome.Evolution.desktop;
text/english=emacs.desktop;gvim.desktop;nvim.desktop;vim.desktop;
text/google-video-pointer=org.gnome.Totem.desktop;vlc.desktop;
text/html=chromium.desktop;firefox.desktop;google-chrome.desktop;org.gnome.Builder.desktop;org.gnome.Epiphany.desktop;org.kde.itinerary.desktop;
text/javascript=org.gnome.Builder.desktop;
text/markdown=okularApplication_md.desktop;org.kde.mobile.okular_md.desktop;
text/mathml=libreoffice-math.desktop;
text/plain=emacs.desktop;gvim.desktop;libreoffice-writer.desktop;nvim.desktop;okularApplication_txt.desktop;org.gnome.gedit.desktop;org.kde.kate.desktop;org.kde.mobile.okular_txt.desktop;vim.desktop;
text/rtf=freeoffice-textmaker.desktop;libreoffice-writer.desktop;
text/spreadsheet=libreoffice-calc.desktop;
text/tab-separated-values=libreoffice-calc.desktop;
text/vnd.trolltech.linguist=linguist.desktop;
text/x-c=emacs.desktop;gvim.desktop;nvim.desktop;org.gnome.Builder.desktop;vim.desktop;
text/x-c++=emacs.desktop;gvim.desktop;nvim.desktop;org.gnome.Builder.desktop;vim.desktop;
text/x-c++hdr=emacs.desktop;gvim.desktop;nvim.desktop;org.gnome.Builder.desktop;vim.desktop;
text/x-c++src=emacs.desktop;gvim.desktop;nvim.desktop;org.gnome.Builder.desktop;vim.desktop;
text/x-changelog=org.gnome.Builder.desktop;
text/x-chdr=emacs.desktop;gvim.desktop;nvim.desktop;org.gnome.Builder.desktop;vim.desktop;
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text/x-cpp=org.gnome.Builder.desktop;
text/x-csrc=emacs.desktop;gvim.desktop;nvim.desktop;org.gnome.Builder.desktop;vim.desktop;
text/x-csv=libreoffice-calc.desktop;
text/x-go=org.gnome.Builder.desktop;
text/x-google-video-pointer=org.gnome.Totem.desktop;vlc.desktop;
text/x-java=emacs.desktop;gvim.desktop;nvim.desktop;vim.desktop;
text/x-javascript=org.gnome.Builder.desktop;
text/x-js=org.gnome.Builder.desktop;
text/x-lua=org.gnome.Builder.desktop;
text/x-makefile=emacs.desktop;gvim.desktop;nvim.desktop;org.gnome.Builder.desktop;vim.desktop;
text/x-markdown=org.gnome.Builder.desktop;
text/x-moc=emacs.desktop;gvim.desktop;nvim.desktop;vim.desktop;
text/x-pascal=emacs.desktop;gvim.desktop;nvim.desktop;vim.desktop;
text/x-patch=org.kde.kompare.desktop;
text/x-perl=org.gnome.Builder.desktop;
text/x-php=org.gnome.Builder.desktop;
text/x-php-source=org.gnome.Builder.desktop;
text/x-pkg-config=org.gnome.Builder.desktop;
text/x-python=org.gnome.Builder.desktop;
text/x-ruby=org.gnome.Builder.desktop;
text/x-sh=org.gnome.Builder.desktop;
text/x-shellscript=org.gnome.Builder.desktop;
text/x-sql=org.gnome.Builder.desktop;
text/x-tcl=emacs.desktop;gvim.desktop;nvim.desktop;vim.desktop;
text/x-tex=emacs.desktop;gvim.desktop;nvim.desktop;vim.desktop;
text/x-vala=org.gnome.Builder.desktop;
text/x-vcard=org.gnome.Evolution.desktop;
text/xml=chromium.desktop;firefox.desktop;google-chrome.desktop;org.gnome.Builder.desktop;
video/3gp=org.gnome.Totem.desktop;vlc.desktop;
video/3gpp=org.gnome.Totem.desktop;vlc.desktop;
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video/dv=org.gnome.Totem.desktop;vlc.desktop;
video/fli=org.gnome.Totem.desktop;vlc.desktop;
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video/x-fli=org.gnome.Totem.desktop;vlc.desktop;
video/x-flic=org.gnome.Totem.desktop;
video/x-flv=org.gnome.Totem.desktop;vlc.desktop;
video/x-m4v=org.gnome.Totem.desktop;vlc.desktop;
video/x-matroska=org.gnome.Totem.desktop;vlc.desktop;
video/x-mjpeg=org.gnome.Totem.desktop;
video/x-mng=okularApplication_kimgio.desktop;org.kde.mobile.okular_kimgio.desktop;
video/x-mpeg=org.gnome.Totem.desktop;vlc.desktop;
video/x-mpeg-system=vlc.desktop;
video/x-mpeg2=org.gnome.Totem.desktop;vlc.desktop;
video/x-ms-asf=org.gnome.Totem.desktop;vlc.desktop;
video/x-ms-asf-plugin=org.gnome.Totem.desktop;vlc.desktop;
video/x-ms-asx=org.gnome.Totem.desktop;vlc.desktop;
video/x-ms-wm=org.gnome.Totem.desktop;vlc.desktop;
video/x-ms-wmv=org.gnome.Totem.desktop;vlc.desktop;
video/x-ms-wmx=org.gnome.Totem.desktop;vlc.desktop;
video/x-ms-wvx=org.gnome.Totem.desktop;vlc.desktop;
video/x-msvideo=org.gnome.Totem.desktop;vlc.desktop;
video/x-nsv=org.gnome.Totem.desktop;vlc.desktop;
video/x-ogm=vlc.desktop;
video/x-ogm+ogg=org.gnome.Totem.desktop;vlc.desktop;
video/x-theora=org.gnome.Totem.desktop;vlc.desktop;
video/x-theora+ogg=org.gnome.Totem.desktop;vlc.desktop;
video/x-totem-stream=org.gnome.Totem.desktop;
x-content/audio-cdda=vlc.desktop;
x-content/audio-player=vlc.desktop;
x-content/blank-bd=org.kde.k3b.desktop;
x-content/blank-cd=org.kde.k3b.desktop;
x-content/blank-dvd=org.kde.k3b.desktop;
x-content/blank-hddvd=org.kde.k3b.desktop;
x-content/unix-software=nautilus-autorun-software.desktop;
x-content/video-dvd=org.gnome.Totem.desktop;vlc.desktop;
x-content/video-svcd=vlc.desktop;
x-content/video-vcd=vlc.desktop;
x-scheme-handler/anydesk=anydesk.desktop;
x-scheme-handler/appstream=org.gnome.Software.desktop;org.manjaro.pamac.manager.desktop;
x-scheme-handler/calendar=org.gnome.Evolution.desktop;
x-scheme-handler/evernote=evernote-client.desktop;
x-scheme-handler/geo=org.gnome.Maps.desktop;
x-scheme-handler/ghelp=yelp.desktop;
x-scheme-handler/help=org.kde.Help.desktop;yelp.desktop;
x-scheme-handler/http=chromium.desktop;firefox.desktop;google-chrome.desktop;org.gnome.Epiphany.desktop;
x-scheme-handler/https=chromium.desktop;firefox.desktop;google-chrome.desktop;org.gnome.Epiphany.desktop;
x-scheme-handler/icy=org.gnome.Totem.desktop;vlc.desktop;
x-scheme-handler/icyx=org.gnome.Totem.desktop;vlc.desktop;
x-scheme-handler/info=org.kde.Help.desktop;yelp.desktop;
x-scheme-handler/irc=org.gnome.Polari.desktop;org.kde.konversation.desktop;
x-scheme-handler/ircs=org.kde.konversation.desktop;
x-scheme-handler/magnet=org.qbittorrent.qBittorrent.desktop;
x-scheme-handler/mailto=org.gnome.Evolution.desktop;org.gnome.Geary.desktop;thunderbird.desktop;
x-scheme-handler/man=org.kde.Help.desktop;yelp.desktop;
x-scheme-handler/memo=org.gnome.Evolution.desktop;
x-scheme-handler/mms=org.gnome.Totem.desktop;vlc.desktop;
x-scheme-handler/mmsh=org.gnome.Totem.desktop;vlc.desktop;
x-scheme-handler/net=org.gnome.Totem.desktop;
x-scheme-handler/pnm=org.gnome.Totem.desktop;
x-scheme-handler/rlogin=ktelnetservice5.desktop;
x-scheme-handler/rtmp=org.gnome.Totem.desktop;vlc.desktop;
x-scheme-handler/rtp=org.gnome.Totem.desktop;vlc.desktop;
x-scheme-handler/rtsp=org.gnome.Totem.desktop;vlc.desktop;
x-scheme-handler/sms=org.kde.kdeconnect.handler.desktop;
x-scheme-handler/snap=org.manjaro.pamac.manager.desktop;snap-handle-link.desktop;
x-scheme-handler/ssh=ktelnetservice5.desktop;
x-scheme-handler/steam=steam.desktop;
x-scheme-handler/steamlink=steam.desktop;
x-scheme-handler/task=org.gnome.Evolution.desktop;
x-scheme-handler/teamviewer8=teamviewer8.desktop;
x-scheme-handler/teamviewerapi=teamviewerapi.desktop;
x-scheme-handler/tel=org.kde.kdeconnect.handler.desktop;
x-scheme-handler/telnet=ktelnetservice5.desktop;
x-scheme-handler/tg=telegramdesktop.desktop;
x-scheme-handler/uvox=org.gnome.Totem.desktop;
x-scheme-handler/vnd.libreoffice.cmis=libreoffice-startcenter.desktop;
x-scheme-handler/web-pamac=web-installer-url-handler.desktop;
x-scheme-handler/webcal=org.gnome.Evolution.desktop;

It is still not working. A remarkable thing is that a loading mouse cursor appears when trying to open, for example, the folder of a download in Firefox. But it disappears shortly after.

Well, the mimeinfo.cache can be very different than others have, especially with the mix of KDE Plasma and Gnome, plus what you have in your home directory … ~/.config/mimeapps.list that also have to have Nautilus instead of nautilus, but, on the other hand, my Gnome install doesn’t have any
inode/directory=org.gnome.Nautilus.desktop; entry in ~/.config/mimeapps.list and never had any issues. The mimeinfo.cache has inode/directory=org.gnome.Nautilus.desktop;ranger.desktop; … so check with N and not n.

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In ~/.config/mimeapps.list I put Nautilus instead of nautilus in both places where it occurs and now the issue is solved.

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After a reboot, although the files did not change (they all use Nautilus instead of nautilus), the issue appears again.

To me this appeared as solved, but if not so, then it means you might have something in startup or at you user level configs that mix things up.
My only idea is that you create a TEST user and see if there you can reproduce the issue and compare the configs.

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If I save the file ~/.config/mimeapps.list, without any change, then next I can use the system locations as usual (so that they open automatically in Nautilus), but only until a system restart. What could be the program/script that overrides ~/.config/mimeapps.list on log-in/system startup?