How to use the thumb button and thumb wheel of mouse?

I am trying a Logitech MX Master 2S mouse with thumb button and thumb wheel, but after I connected the mouse, I cannot use its thumb button and thumb wheel.

I tried to use solaar but all the options are locked.

Please refer to their documentation about Solaar Usage | Solaar
As stated there

So you should be able to click on the lock sign to unlock it, and make the change when the device is connected via USB.

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