Screenshot shows a mono source using input and output channel maps FL,FR and does not look anything like my suggestion of how to use remap module
I could connect Scarlett Capture AUX1 → mono source input FR manually. But this didn’t help. During the test call only the left channel audio (voice) arrived.
If Skype is using FL channel only and ignoring FR channel I would not expect it to help
Skype used to have decent audio, until Microsoft bought it out
Skype does not have an issue when used as intended with one microphone, but users who want to mix more than one audio source to Skype callers will need to customise audio server configuration