USB audio device not set as default

Please post more information about audio devices and sinks (outputs)

pactl list cards
pactl list sinks short
pactl get default-sink

The simplest way to ensure audio plays to a specific device is to change the card profiles of unused devices to Off

Or install pavucontrol-qt to control audio streams
Configuration tab (pavucontrol --tab =5) to change card Profiles
Playback tab pavucontrol --tab =1) to select from multiple playback devices

Audio streams would have to play through EasyEffects

Default device management · wwmm/easyeffects · Discussion #1836 · GitHub
wwmm on Sep 18, 2022 Maintainer

My expectation would be that the easy effects sync/source would be the default system wide so that all applications would use them forcing any effects to be applied.

In its default configuration EasyEffects tries to use the default system input/output device. If you set our own devices as default there is a chance that in EasyEffects initialization phase PipeWire will report our own devices as the default devices and as EasyEffects can’t play to / record from itself it won’t know anymore which device it should use. This has happened to some users.