Ongoing /dev/ttyUSB0D CH341 serial dropping issue

Having a problem with /dev/ttyUSB0D cycling and dropping. This is an ESP32 board, powered by separate power. When connected to system it will cycle endlessly like seen below. This happens on Kernels 5.10-5.19

Currently on;
Linux slip 5.10.141-1-MANJARO #1 SMP PREEMPT Mon Sep 5 10:15:26 UTC 2022 x86_64 GNU/Linux

Have tried multiple hubs, powered and unpowered, all 3 USB ports on machine. 8 different cables. I have tried the solutions mentioned in other threads about removing brltty ( Can't connect serial port - Error: ch341-uart disconnected from ttyUSB0 - #2 by iracigt ) and while it was installed it no longer is.

If I connect older/different boards based on cp210x they do not cycle like this.

Anyone have a suggestion on how to troubleshoot further? I have tried 2 different CH341 based boards, same result.

[Thu Sep 15 09:34:15 2022] usb 1-1: new full-speed USB device number 55 using xhci_hcd
[Thu Sep 15 09:34:15 2022] usb 1-1: New USB device found, idVendor=1a86, idProduct=7523, bcdDevice=81.32
[Thu Sep 15 09:34:15 2022] usb 1-1: New USB device strings: Mfr=0, Product=2, SerialNumber=0
[Thu Sep 15 09:34:15 2022] usb 1-1: Product: USB Serial
[Thu Sep 15 09:34:15 2022] ch341 1-1:1.0: ch341-uart converter detected
[Thu Sep 15 09:34:15 2022] usb 1-1: ch341-uart converter now attached to ttyUSB0
[Thu Sep 15 09:34:24 2022] usb 1-1: USB disconnect, device number 55
[Thu Sep 15 09:34:24 2022] ch341-uart ttyUSB0: ch341-uart converter now disconnected from ttyUSB0
[Thu Sep 15 09:34:24 2022] ch341 1-1:1.0: device disconnected
[Thu Sep 15 09:34:26 2022] usb 1-1: new full-speed USB device number 56 using xhci_hcd
[Thu Sep 15 09:34:26 2022] usb 1-1: New USB device found, idVendor=1a86, idProduct=7523, bcdDevice=81.32
[Thu Sep 15 09:34:26 2022] usb 1-1: New USB device strings: Mfr=0, Product=2, SerialNumber=0
[Thu Sep 15 09:34:26 2022] usb 1-1: Product: USB Serial
[Thu Sep 15 09:34:26 2022] ch341 1-1:1.0: ch341-uart converter detected
[Thu Sep 15 09:34:26 2022] usb 1-1: ch341-uart converter now attached to ttyUSB0
[Thu Sep 15 09:34:30 2022] usb 1-1: USB disconnect, device number 56
[Thu Sep 15 09:34:30 2022] ch341-uart ttyUSB0: ch341-uart converter now disconnected from ttyUSB0
[Thu Sep 15 09:34:30 2022] ch341 1-1:1.0: device disconnected
[Thu Sep 15 09:34:32 2022] usb 1-1: new full-speed USB device number 57 using xhci_hcd
[Thu Sep 15 09:34:32 2022] usb 1-1: New USB device found, idVendor=1a86, idProduct=7523, bcdDevice=81.32
[Thu Sep 15 09:34:32 2022] usb 1-1: New USB device strings: Mfr=0, Product=2, SerialNumber=0
[Thu Sep 15 09:34:32 2022] usb 1-1: Product: USB Serial
[Thu Sep 15 09:34:32 2022] ch341 1-1:1.0: ch341-uart converter detected
[Thu Sep 15 09:34:32 2022] usb 1-1: ch341-uart converter now attached to ttyUSB0

Device info

[rahlquist@slip ~]$ lsusb
Bus 002 Device 001: ID 1d6b:0003 Linux Foundation 3.0 root hub
Bus 001 Device 004: ID 06cb:00c9 Synaptics, Inc. 
Bus 001 Device 003: ID 0408:5368 Quanta Computer, Inc. HP TrueVision HD Camera
Bus 001 Device 006: ID 8087:0026 Intel Corp. AX201 Bluetooth
Bus 001 Device 088: ID 1a86:7523 QinHeng Electronics CH340 serial converter
Bus 001 Device 001: ID 1d6b:0002 Linux Foundation 2.0 root hub
[rahlquist@slip ~]$ lsusb -v -d 1a86:7523

Bus 001 Device 097: ID 1a86:7523 QinHeng Electronics CH340 serial converter
Couldn't open device, some information will be missing
Device Descriptor:
  bLength                18
  bDescriptorType         1
  bcdUSB               1.10
  bDeviceClass          255 Vendor Specific Class
  bDeviceSubClass         0 
  bDeviceProtocol         0 
  bMaxPacketSize0         8
  idVendor           0x1a86 QinHeng Electronics
  idProduct          0x7523 CH340 serial converter
  bcdDevice           81.32
  iManufacturer           0 
  iProduct                2 USB Serial
  iSerial                 0 
  bNumConfigurations      1
  Configuration Descriptor:
    bLength                 9
    bDescriptorType         2
    wTotalLength       0x0027
    bNumInterfaces          1
    bConfigurationValue     1
    iConfiguration          0 
    bmAttributes         0x80
      (Bus Powered)
    MaxPower              100mA
    Interface Descriptor:
      bLength                 9
      bDescriptorType         4
      bInterfaceNumber        0
      bAlternateSetting       0
      bNumEndpoints           3
      bInterfaceClass       255 Vendor Specific Class
      bInterfaceSubClass      1 
      bInterfaceProtocol      2 
      iInterface              0 
      Endpoint Descriptor:
        bLength                 7
        bDescriptorType         5
        bEndpointAddress     0x82  EP 2 IN
        bmAttributes            2
          Transfer Type            Bulk
          Synch Type               None
          Usage Type               Data
        wMaxPacketSize     0x0020  1x 32 bytes
        bInterval               0
      Endpoint Descriptor:
        bLength                 7
        bDescriptorType         5
        bEndpointAddress     0x02  EP 2 OUT
        bmAttributes            2
          Transfer Type            Bulk
          Synch Type               None
          Usage Type               Data
        wMaxPacketSize     0x0020  1x 32 bytes
        bInterval               0
      Endpoint Descriptor:
        bLength                 7
        bDescriptorType         5
        bEndpointAddress     0x81  EP 1 IN
        bmAttributes            3
          Transfer Type            Interrupt
          Synch Type               None
          Usage Type               Data
        wMaxPacketSize     0x0008  1x 8 bytes
        bInterval               1