Strange gnome issues on some programs

There is an update for that BIOS MSI MPG B550I GAMING EDGE WIFI AMD AM4 DDR4 M.2 USB 3.2 Gen 2 HDMI ITX Gaming Motherboard probably not chose the beta one, but the latest one before that.

You should switch to either 5.13 or 5.14 as AFAIK have better support for AMD GPUs.
Other than that, not sure what the issue could be as you run on X11 … Is this happening only with Qt applications?