When I started playing Salt&Sanctuary again, I had no Troubles at all. Now after defeating one of the Bosses in the Sunken Area, my dGPU suddenly loses the signal to the Display. This requires me to reboot the Computer.
At first I thought that a bug in Xfce was the cause of this, after this occurred with IcwWM, I figured out nope it is Firefox and/or paused videos was doing this.
I’m not sure if FF only does this with this Game only, but may be an Issue with some other one or what. But it is something to try.
I hope this helps everyone.