I’ve been testing pipewire version 0.3.27 for more than a week now. (XFCE with 5.12 kernel) No problems so far, it works much better than PulseAudio. Pipewire even fixed a very nasty issue I was having on PulseAudio: Bluetooth sound and microphone at the same time - #7 by mynewlaptop
I heard that Fedora is migrating to Pipewire. I recommend Manjaro do the same.