Playing on Preset 7 of 10 on 2560x1440 and Antialiasing off (check render scale setting in the advanced settings, reducing it from 200% to 100% gives a lot of fps)
Using DX9 as the option for DX11 is not offered here - if there is a way to make it work, I would really like to give it a try
My fps are between 25 and 160 depending on the area I am in. General flying gives between 30 and 50 fps.
edit: Today’s update to Mesa 17.0.2 in testing branch seems to have improved the fps a little bit (definitely not much, but still)
Well, I used the PoL Battle.net script, modified it for 64bit, added some things that are installed in WoW, SC2 and Diablo III scripts, and manually installed vcrun2015 with winetricks during the installation as it still is not available in PoL